About HAE

What is hereditary angioedema (HAE)?

HAE is a very rare genetic disorder that occurs in about 1 in 10,000 to 1 in 50,000 people worldwide.

The clinical course of HAE attacks is unpredictable.

HAE is characterized by episodes of swelling (edema attacks) in different areas of the skin or the internal organs.

• Edema of the skin occurs mainly in the face (e.g., lips, eyelids), although the extremities and genitals are also often affected
• Edema of the mucous membranes affects the larynx, nose, or tongue
• Abdominal pain is reported by 70-80% of patients with HAE